Fig. 1 · Structure
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CP 461 free base
Apoptosi
CP 461 free base is a pro-apoptotic compound that inhibits cyclic guanosine monophosphate phosphodiesterase, leading to selective induction of apoptosis in cancer cell lines. This compound demonstrates significant growth inhibitory effects against various human tumor cell lines in vitro, while sparing normal cells. CP 461 free base is valuable for research applications targeting renal cell carcinoma, prostate cancer, and Crohn's disease.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 227619-92-3 |
| Applications | Apoptosi |
| Formula | C25H21FN2O |
| Molecular Weight | 384.45 |
| Synonyms | OSI-461 free base |
| SMILES | O=C(NCC1=CC=CC=C1)CC(C2=CC(F)=CC=C2/3)=C(C)C3=C\C4=CC=NC=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.