CP-465022 maleate is a potent, selective noncompetitive antagonist of the AMPA receptor, exhibiting anticonvulsant properties. It effectively inhibits kainate-induced responses in rat cortical neurons with an IC50 of 25 nM. This compound serves as a valuable research tool to explore the role of AMPA receptors in both physiological and pathophysiological contexts.
CP-465022 maleate is a potent, selective noncompetitive antagonist of the AMPA receptor, exhibiting anticonvulsant properties. It effectively inhibits kainate-induced responses in rat cortical neurons with an IC50 of 25 nM. This compound serves as a valuable research tool to explore the role of AMPA receptors in both physiological and pathophysiological contexts.
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