Fig. 1 · Structure
Documents & Downloads
CP5V
PROTAC Cdc20 PROTAC
CP5V is a PROTAC that targets Cdc20 for degradation through the recruitment of the von Hippel-Lindau (VHL) complex. By facilitating the ubiquitination of Cdc20, CP5V promotes proteasomal degradation, leading to mitotic inhibition. This compound has significant applications in research focused on cancer cell proliferation and cell cycle regulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Degrader |
| CAS Number | 2509359-75-3 |
| Applications | PROTAC Cdc20 PROTAC |
| Formula | C46H66Cl3N9O12S |
| Molecular Weight | 1075.49 |
| SMILES | ClC(Cl)(Cl)C(NC(OCCCNC(CCOCCOCCOCCOCCOCCC(N[C@@H](C(C)(C)C)C(N1C[C@H](O)C[C@H]1C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)=O)=O)=O)=O)NC4=NC=CC=N4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.