CPF-7, a precursor fragment of caerulein, functions as an insulin-releasing peptide by stimulating insulin secretion. Additionally, it promotes epithelial-mesenchymal transition through the upregulation of Snai1 expression in PANC-1 ductal cells and induces exocrine plasticity by enhancing Ngn3 expression. This peptide is valuable for research applications focused on the mechanisms of type 2 diabetes and pancreatic cell plasticity.
CPF-7, a precursor fragment of caerulein, functions as an insulin-releasing peptide by stimulating insulin secretion. Additionally, it promotes epithelial-mesenchymal transition through the upregulation of Snai1 expression in PANC-1 ductal cells and induces exocrine plasticity by enhancing Ngn3 expression. This peptide is valuable for research applications focused on the mechanisms of type 2 diabetes and pancreatic cell plasticity.
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