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CQ-16

Small Molecule Drug Conjugate

CQ-16 is an orally active small molecule drug conjugate (SMDC) that targets prostate-specific membrane antigen (PSMA). This compound demonstrates selective antiproliferative activity against PSMA-positive prostate cells while sparing PSMA-negative cells. Additionally, CQ-16 exhibits potent PARP inhibitory activity with an IC50 value of 1 nM, making it a valuable tool for research applications focused on prostate cancer therapy and PARP-related pathways.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	3024354-59-1
Applications	Small Molecule Drug Conjugate
Formula	C₄₀H₄₇FN₈O₁₂
Molecular Weight	850.85
SMILES	O=C1NN=C(C2=CC=CC=C21)CC3=CC=C(C(C(N4CCN(CC4)C(C5(NC(CCC(NCCCC[C@H](NC(N[C@H](C(O)=O)CCC(O)=O)=O)C(O)=O)=O)=O)CC5)=O)=O)=C3)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.