Documents & Downloads

CQ3196

RIOK2 Inhibitor

CQ3196 is a potent RIOK2 inhibitor with a Kd of 14 nM, effectively blocking its ATPase activity with an IC50 of 72 nM. This compound demonstrates significant anti-proliferative effects on gastric cancer cell lines, notably inducing apoptosis in HGC-27 and AGS cells. Additionally, CQ3196 inhibits key downstream signaling pathways by reducing phosphorylation of mTOR and AKT, thereby modulating ribosome function and protein synthesis. Its capabilities make CQ3196 a valuable tool for in vitro and in vivo research in gastric cancer biology.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3105591-09-8
Applications	RIOK2 Inhibitor
Formula	C₃₀H₃₀F₃N₇O₂
Molecular Weight	577.60
SMILES	COC1=CC=C(C=N1)C2=CC=C3N=C(C4=C(N(N=N4)C5=CC=C(C(C(F)(F)F)=C5)N6CCC(N(C)C)CC6)C3=C2)OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.