Fig. 1 · Structure
Documents & Downloads
CR 665
κ-opioid Agonist
CR 665 is a peripherally selective κ-opioid agonist that targets the kappa opioid receptor, exhibiting an EC50 value of 10.9 nM. This compound is primarily utilized in research focused on peripheral pain mechanisms, making it a valuable tool for studying pain modulation and analgesic pathways. Its selective action offers potential for exploring new analgesic therapies with reduced central side effects.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 228546-92-7 |
| Applications | κ-opioid Agonist |
| Formula | C36H49N9O4 |
| Molecular Weight | 671.83 |
| Synonyms | JNJ 38488502; FE 200665 |
| SMILES | [C@@H](CC1=CC=CC=C1)(C(N[C@@H](C(N[C@@H](C(NCC=2C=CN=CC2)=O)CCCNC(=N)N)=O)CCCC)=O)NC([C@@H](CC3=CC=CC=C3)N)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.