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CRBN ligand-1

Ligands for E3 Ligase

CRBN ligand-1 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound plays a critical role in mediating protein degradation through the ubiquitin-proteasome pathway, making it an important tool for studying protein homeostasis and cellular signaling mechanisms. It is utilized in research applications focused on targeted protein degradation and the development of novel therapeutics for diseases related to dysregulated protein dynamics.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	3032314-67-0
Applications	Ligands for E3 Ligase
Formula	C₁₁H₁₂N₂O₂
Molecular Weight	204.23
SMILES	O=C1NC(C(CC1)NC2=CC=CC=C2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.