Documents & Downloads

CRBN ligand-12

E3 Ubiquitin Ligase Ligand

CRBN ligand-12 is a CRBN-type E3 ubiquitin ligase ligand that functions by promoting ubiquitination processes. This compound is instrumental in the development of proteolysis-targeting chimeras (PROTACs), enabling targeted protein degradation. Its capacity to influence the ubiquitin-proteasome pathway makes it a valuable tool in cellular biology and therapeutic research applications.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2820501-20-8
Applications	E3 Ubiquitin Ligase Ligand
Formula	C₁₅H₁₆F₂N₂O₃
Molecular Weight	310.30
SMILES	O=C(C(C1=C(F)C=C(N2CC(CO)C2)C=C1F)CC3)NC3=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.