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CRBN ligand-14

Ligands for E3 Ligase

CRBN ligand-14 is a ligand targeting the CRBN E3 ubiquitin ligase, facilitating the formation of PROTACs (PROteolysis TArgeting Chimeras). This compound plays a crucial role in targeted protein degradation, enabling the selective elimination of proteins of interest within cellular systems. It is particularly valuable in drug discovery and development, providing insights into protein regulation and therapeutic interventions in various diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	3050687-74-3
Applications	Ligands for E3 Ligase
Formula	C₁₁H₉BrFNO₂
Molecular Weight	286.10
SMILES	BrC1=CC=CC(C2C(NC(CC2)=O)=O)=C1F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.