Documents & Downloads

CRBN ligand-162

Ligands for E3 Ligase

CRBN ligand-162 is a ligand for the CRBN-type E3 ubiquitin ligase, facilitating the targeted degradation of proteins through the ubiquitin-proteasome system. This compound is utilized in the design and synthesis of PROTACs (Proteolysis Targeting Chimeras), which are powerful tools for selective protein degradation in various biological research applications. Its utilization promotes advancements in understanding protein function and therapeutic interventions in diseases linked to protein dysregulation.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	3036607-75-4
Applications	Ligands for E3 Ligase
Formula	C₁₂H₁₁BrClNO₂
Molecular Weight	316.58
SMILES	O=C(C(C1=C(C)C=C(Br)C=C1Cl)CC2)NC2=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.