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CRBN ligand-17

Ligands for E3 Ligase

CRBN ligand-17 is an E3 ubiquitin ligase ligand that targets the cereblon (CRBN) substrate recognition domain. This compound is essential for the design and synthesis of PROTACs (proteolysis-targeting chimeras), which facilitate targeted protein degradation. Its application in research includes studying protein regulation mechanisms and investigating therapeutic strategies for various diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	3050687-80-1
Applications	Ligands for E3 Ligase
Formula	C₁₂H₉BrF₃NO₂
Molecular Weight	336.10
SMILES	BrC1=CC=CC(C2CCC(NC2=O)=O)=C1C(F)(F)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.