CRBN ligand-190

Catalog No.: A80664
Ligands for E3 Ligase
CRBN ligand-190 is a ligand for the CRBN-type E3 ubiquitin ligase, facilitating the targeted ubiquitination and degradation of proteins. This compound is instrumental in the development of PROTACs (proteolysis-targeting chimeras), notably for synthesizing PROTAC HPK1 Degrader-7. Its utility in protein degradation strategies makes it a valuable tool for research in targeted therapy and protein homeostasis.
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Adooq Products cited in reputable paper
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Biological Activity
DescriptionCRBN ligand-190 is a ligand for the CRBN-type E3 ubiquitin ligase, facilitating the targeted ubiquitination and degradation of proteins. This compound is instrumental in the development of PROTACs (proteolysis-targeting chimeras), notably for synthesizing PROTAC HPK1 Degrader-7. Its utility in protein degradation strategies makes it a valuable tool for research in targeted therapy and protein homeostasis.
Product Information
Catalog NumA80664
FormulaC10H9FN2O2
Molecular Weight208.19
CAS Number1543013-96-2
SMILESFC1=CC(N(C(N2)=O)CCC2=O)=CC=C1
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