CRBN Ligand-191 is an E3 ligase ligand that targets the cereblon (CRBN) protein, facilitating ubiquitination and subsequent degradation of tagged substrates. This compound is essential in the synthesis of PROTACs, such as the PROTAC ALK degrader-4, which enables selective degradation of specific oncoproteins. Researchers can utilize CRBN Ligand-191 to explore targeted protein degradation mechanisms and study protein homeostasis in various biological contexts.
CRBN Ligand-191 is an E3 ligase ligand that targets the cereblon (CRBN) protein, facilitating ubiquitination and subsequent degradation of tagged substrates. This compound is essential in the synthesis of PROTACs, such as the PROTAC ALK degrader-4, which enables selective degradation of specific oncoproteins. Researchers can utilize CRBN Ligand-191 to explore targeted protein degradation mechanisms and study protein homeostasis in various biological contexts.
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