CRBN ligand-194 functions as a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be conjugated to a target protein ligand through a linker to create a PROTAC (proteolysis-targeting chimera). Its use in research enables the selective degradation of target proteins, making it a valuable tool for studying protein dynamics and therapeutic interventions in various diseases.
CRBN ligand-194 functions as a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be conjugated to a target protein ligand through a linker to create a PROTAC (proteolysis-targeting chimera). Its use in research enables the selective degradation of target proteins, making it a valuable tool for studying protein dynamics and therapeutic interventions in various diseases.
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