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CRBN ligand-201

Ligand for E3 Ligase

CRBN ligand-201 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be utilized to link with target protein ligands through a suitable linker, enabling the formation of proteolysis-targeting chimeras (PROTACs). Its application is primarily in the fields of targeted protein degradation and drug discovery, offering insights into cellular regulation and therapeutic interventions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2766179-06-8
Applications	Ligand for E3 Ligase
Formula	C₁₇H₂₀N₄O₂
Molecular Weight	312.37
SMILES	O=C1NC(=O)CCN1C=2C=CC=C3NC(=CC32)C4CCNCC4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.