CRBN ligand-204

Catalog No.: A80697
Ligand for E3 Ligase
CRBN ligand-204 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound facilitates the recruitment of cereblon, enabling targeted protein degradation through the formation of proteolysis-targeting chimeras (PROTACs) when linked to a target protein ligand. CRBN ligand-204 is valuable in research applications involving the modulation of protein levels and the study of ubiquitin-mediated pathways.
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Biological Activity
DescriptionCRBN ligand-204 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound facilitates the recruitment of cereblon, enabling targeted protein degradation through the formation of proteolysis-targeting chimeras (PROTACs) when linked to a target protein ligand. CRBN ligand-204 is valuable in research applications involving the modulation of protein levels and the study of ubiquitin-mediated pathways.
Product Information
Catalog NumA80697
FormulaC11H10FN3O3
Molecular Weight251.22
CAS Number1910957-41-3
SMILESO=C(NC1C(=O)NC(=O)CC1)C2=NC=C(F)C=C2
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