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CRBN ligand-208

Ligand for E3 Ligase

CRBN ligand-208 is a small-molecule ligand targeting the E3 ubiquitin ligase cereblon (CRBN). It is designed to facilitate the recruitment of CRBN to target proteins, enabling targeted protein degradation through PROTAC technology. This compound is applicable in research focusing on protein regulation and cellular signaling pathways, providing a valuable tool for drug discovery and development.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2760376-01-8
Applications	Ligand for E3 Ligase
Formula	C₁₂H₁₀FNO₄
Molecular Weight	251.21
SMILES	O=C(O)C1=CC=C(F)C(=C1)C2C(=O)NC(=O)CC2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.