CRBN ligand-227

Catalog No.: A81211
Ligand for E3 Ligase
CRBN ligand-227 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN). It facilitates the recruitment of the cereblon protein, enabling targeted protein degradation through PROTAC (Proteolysis Targeting Chimera) technology. This compound is instrumental in research applications focused on elucidating protein turnover and modulating cellular pathways linked to disease.
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Adooq Products cited in reputable paper
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Biological Activity
DescriptionCRBN ligand-227 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN). It facilitates the recruitment of the cereblon protein, enabling targeted protein degradation through PROTAC (Proteolysis Targeting Chimera) technology. This compound is instrumental in research applications focused on elucidating protein turnover and modulating cellular pathways linked to disease.
Product Information
Catalog NumA81211
FormulaC12H12FN3O3
Molecular Weight265.24
CAS Number1482078-60-3
SMILESO=C(NC1C(=O)NC(=O)CC1)C2=CC=C(N)C=C2F
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