CRBN ligand-228 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein for targeted protein degradation. It can be conjugated with a target protein ligand through a linker to generate a PROTAC (proteolysis-targeting chimera). This compound is instrumental in studies aimed at exploring the degradation of specific proteins and developing novel therapeutic strategies in cancer and other diseases.
CRBN ligand-228 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein for targeted protein degradation. It can be conjugated with a target protein ligand through a linker to generate a PROTAC (proteolysis-targeting chimera). This compound is instrumental in studies aimed at exploring the degradation of specific proteins and developing novel therapeutic strategies in cancer and other diseases.
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