CRBN ligand-229 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be successfully linked to a target protein ligand through a linker to create a PROTAC (proteolysis-targeting chimera). Research applications of CRBN ligand-229 include targeted protein degradation and the study of ubiquitin-mediated proteostasis pathways.
CRBN ligand-229 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be successfully linked to a target protein ligand through a linker to create a PROTAC (proteolysis-targeting chimera). Research applications of CRBN ligand-229 include targeted protein degradation and the study of ubiquitin-mediated proteostasis pathways.
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