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CRBN ligand-231

Ligand for E3 Ligase

CRBN ligand-231 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be utilized to create a PROTAC (Proteolysis Targeting Chimeras) by linking it to a target protein ligand through a suitable linker. CRBN ligand-231 is instrumental in research applications focused on targeted protein degradation and the study of ubiquitin-proteasome pathway mechanisms.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	3031608-09-7
Applications	Ligand for E3 Ligase
Formula	C₁₅H₁₈FN₃O₂
Molecular Weight	291.33
SMILES	O=C1NC(=O)C(C2=CC(=CC=C2F)N3CCNCC3)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.