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CRBN ligand-232

Ligand for E3 Ligase

CRBN ligand-232 is a ligand for the E3 ubiquitin ligase cerberlon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be conjugated with a target protein ligand through a linker to produce a PROTAC, enabling targeted protein degradation. Its application is particularly relevant in studies focusing on protein modulation and therapeutic intervention in various disease models.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	3026676-91-2
Applications	Ligand for E3 Ligase
Formula	C₁₇H₁₅BrFNO₃
Molecular Weight	380.21
SMILES	O=C1C=2C(F)=CC(Br)=CC2CN1CC3=CC=C(OC)C=C3OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.