CRBN ligand-251 is an E3 ubiquitin ligase cereblon (CRBN) ligand that facilitates the recruitment of the cereblon protein. This compound serves as a crucial component for the development of PROTACs (proteolysis-targeting chimeras) by linking to target protein ligands through a suitable linker. Its application in chemical biology enables the modulation of protein degradation pathways, providing a valuable tool for studying protein function and therapeutic intervention in various diseases.
CRBN ligand-251 is an E3 ubiquitin ligase cereblon (CRBN) ligand that facilitates the recruitment of the cereblon protein. This compound serves as a crucial component for the development of PROTACs (proteolysis-targeting chimeras) by linking to target protein ligands through a suitable linker. Its application in chemical biology enables the modulation of protein degradation pathways, providing a valuable tool for studying protein function and therapeutic intervention in various diseases.
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