Fig. 1 · Structure

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CRBN ligand-256

Ligand for E3 Ligase

CRBN ligand-256 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of this essential protein. This compound can be utilized in the development of PROTACs by linking it to a target protein ligand through a suitable linker. CRBN ligand-256 is instrumental in studies focused on targeted protein degradation and the modulation of various biological pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 2925095-25-4
Applications Ligand for E3 Ligase
Formula C13H10BrN3O2
Molecular Weight 320.15
SMILES
O=C1NC(=O)CCN1C2=CC(Br)=C3N=CC=CC3=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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