CRBN ligand-261 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), which facilitates the recruitment of CRBN to target proteins. This compound can be utilized in the design of PROTACs (proteolysis-targeting chimeras) by linking it to a target protein ligand through a suitable linker. Its applications in chemical biology include targeted degradation of specific proteins, thereby advancing research in drug development and protein homeostasis.
CRBN ligand-261 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), which facilitates the recruitment of CRBN to target proteins. This compound can be utilized in the design of PROTACs (proteolysis-targeting chimeras) by linking it to a target protein ligand through a suitable linker. Its applications in chemical biology include targeted degradation of specific proteins, thereby advancing research in drug development and protein homeostasis.
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