CRBN ligand-264 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), enabling targeted recruitment of the CRBN protein. This compound is instrumental in the development of proteolysis-targeting chimeras (PROTACs) by linking to target protein ligands through a suitable linker, facilitating selective degradation of proteins in cellular environments. Its application in research may enhance studies related to protein regulation and therapeutic interventions targeting protein homeostasis.
CRBN ligand-264 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), enabling targeted recruitment of the CRBN protein. This compound is instrumental in the development of proteolysis-targeting chimeras (PROTACs) by linking to target protein ligands through a suitable linker, facilitating selective degradation of proteins in cellular environments. Its application in research may enhance studies related to protein regulation and therapeutic interventions targeting protein homeostasis.
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