CRBN ligand-271

Catalog No.: A81064
Ligand for E3 Ligase
CRBN ligand-271 is a targeted ligand for the E3 ubiquitin ligase cereblon (CRBN). It functions by recruiting the cereblon protein, enabling the formation of PROTACs (proteolysis-targeting chimeras) when linked to a specific target protein ligand through a suitable linker. This compound is valuable for studies involving targeted protein degradation and cellular regulation, assisting researchers in exploring novel therapeutic approaches in cancer and other diseases.
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Adooq Products cited in reputable paper
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Biological Activity
DescriptionCRBN ligand-271 is a targeted ligand for the E3 ubiquitin ligase cereblon (CRBN). It functions by recruiting the cereblon protein, enabling the formation of PROTACs (proteolysis-targeting chimeras) when linked to a specific target protein ligand through a suitable linker. This compound is valuable for studies involving targeted protein degradation and cellular regulation, assisting researchers in exploring novel therapeutic approaches in cancer and other diseases.
Product Information
Catalog NumA81064
FormulaC13H10BrN3O2
Molecular Weight320.15
CAS Number2925085-92-1
SMILESO=C1NC(=O)CCN1C=2C=C(Br)C=C3N=CC=CC32
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