CRBN ligand-287

Catalog No.: A81257
Ligand for E3 Ligase
CRBN ligand-287 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to specific target proteins. This compound is designed for use in the development of proteolysis-targeting chimeras (PROTACs), enabling targeted degradation of proteins for therapeutic applications. Its ability to effectively modulate protein levels highlights its potential in various biological research and drug discovery endeavors.
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Adooq Products cited in reputable paper
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Biological Activity
DescriptionCRBN ligand-287 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to specific target proteins. This compound is designed for use in the development of proteolysis-targeting chimeras (PROTACs), enabling targeted degradation of proteins for therapeutic applications. Its ability to effectively modulate protein levels highlights its potential in various biological research and drug discovery endeavors.
Product Information
Catalog NumA81257
FormulaC12H10F3NO3
Molecular Weight273.21
CAS Number2933136-78-6
SMILESO=C1NC(=O)C(C2=CC=C(O)C(=C2)C(F)(F)F)CC1
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