CRBN ligand-291 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), functioning by selectively recruiting the CRBN protein. It serves as a valuable component in the construction of PROTACs (proteolysis-targeting chimeras) when linked to a target protein ligand via a suitable linker. This compound is essential for studies focused on targeted protein degradation and elucidating cellular mechanisms involving the ubiquitin-proteasome system.
CRBN ligand-291 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), functioning by selectively recruiting the CRBN protein. It serves as a valuable component in the construction of PROTACs (proteolysis-targeting chimeras) when linked to a target protein ligand via a suitable linker. This compound is essential for studies focused on targeted protein degradation and elucidating cellular mechanisms involving the ubiquitin-proteasome system.
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