CRBN ligand-294

Catalog No.: A81231
Ligand for E3 Ligase
CRBN ligand-294 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be utilized in the development of PROTACs (Proteolysis Targeting Chimeras) by linking it to a specific target protein ligand through a suitable linker. Its application in targeted protein degradation offers potential for advancing therapeutic strategies in various diseases.
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Adooq Products cited in reputable paper
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Biological Activity
DescriptionCRBN ligand-294 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be utilized in the development of PROTACs (Proteolysis Targeting Chimeras) by linking it to a specific target protein ligand through a suitable linker. Its application in targeted protein degradation offers potential for advancing therapeutic strategies in various diseases.
Product Information
Catalog NumA81231
FormulaC12H10BrN3O2
Molecular Weight308.14
CAS Number2925092-50-6
SMILESO=C1NC(=O)CCN1C=2C=C(Br)C=3NC=CC3C2
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