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CRBN ligand-296

Ligand for E3 Ligase

CRBN ligand-296 is a ligand for the E3 ubiquitin ligase cereblon (CRBN). It facilitates the recruitment of CRBN to target proteins, enabling targeted protein degradation through PROTAC (Proteolysis Targeting Chimeras) technology. This compound is valuable for research applications focused on ubiquitin-mediated proteolysis and the development of novel therapeutic strategies for various diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925087-79-0
Applications	Ligand for E3 Ligase
Formula	C₁₂H₁₀BrN₃O₂
Molecular Weight	308.14
SMILES	O=C1NC(=O)CCN1C2=CC(Br)=CC=3C=CNC32

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.