CRBN ligand-299

Catalog No.: A80962
Ligand for E3 Ligase
CRBN ligand-299 serves as an E3 ubiquitin ligase ligand that selectively recruits the cereblon (CRBN) protein. This compound can be utilized to conjugate with target protein ligands through a linker, facilitating the development of proteolysis-targeting chimeras (PROTACs) for targeted protein degradation studies. As such, it is valuable for research focused on modulating protein levels and studying cellular processes influenced by ubiquitination pathways.
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Biological Activity
DescriptionCRBN ligand-299 serves as an E3 ubiquitin ligase ligand that selectively recruits the cereblon (CRBN) protein. This compound can be utilized to conjugate with target protein ligands through a linker, facilitating the development of proteolysis-targeting chimeras (PROTACs) for targeted protein degradation studies. As such, it is valuable for research focused on modulating protein levels and studying cellular processes influenced by ubiquitination pathways.
Product Information
Catalog NumA80962
FormulaC12H10BrN3O2
Molecular Weight308.14
CAS Number2925079-23-6
SMILESO=C1NC(=O)CCN1C=2C=C(Br)C=C3NC=CC32
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