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CRBN ligand-304

Ligand for E3 Ligase

CRBN ligand-304 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be conjugated with a target protein ligand through a linker, enabling the formation of a PROTAC (Proteolysis Targeting Chimera). CRBN ligand-304 is instrumental in studying protein degradation pathways and the development of targeted therapeutics in cancer research and other therapeutic areas.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925102-45-8
Applications	Ligand for E3 Ligase
Formula	C₁₂H₁₁N₅O₂
Molecular Weight	257.25
SMILES	O=C1NC(=O)CCN1C=2C=C(N)C=C3N=CN=CC32

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.