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CRBN ligand-315

Ligand for E3 Ligase

CRBN ligand-315 is an E3 ubiquitin ligase cereblon (CRBN) ligand that facilitates the recruitment of cereblon protein. This compound can be conjugated to a target protein ligand via a linker to create a PROTAC (Proteolysis Targeting Chimera). Its utility in targeted protein degradation makes it a valuable tool for studying protein function and developing potential therapeutics in the field of cellular biology.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925081-83-8
Applications	Ligand for E3 Ligase
Formula	C₁₂H₉BrN₄O₂
Molecular Weight	321.13
SMILES	O=C1NC(=O)CCN1C=2C=C(Br)C=3N=CN=CC3C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.