CRBN ligand-315

Catalog No.: A81208
Ligand for E3 Ligase
CRBN ligand-315 is an E3 ubiquitin ligase cereblon (CRBN) ligand that facilitates the recruitment of cereblon protein. This compound can be conjugated to a target protein ligand via a linker to create a PROTAC (Proteolysis Targeting Chimera). Its utility in targeted protein degradation makes it a valuable tool for studying protein function and developing potential therapeutics in the field of cellular biology.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Nature Volume 622 Issue 7982 (2023)
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Biological Activity
DescriptionCRBN ligand-315 is an E3 ubiquitin ligase cereblon (CRBN) ligand that facilitates the recruitment of cereblon protein. This compound can be conjugated to a target protein ligand via a linker to create a PROTAC (Proteolysis Targeting Chimera). Its utility in targeted protein degradation makes it a valuable tool for studying protein function and developing potential therapeutics in the field of cellular biology.
Product Information
Catalog NumA81208
FormulaC12H9BrN4O2
Molecular Weight321.13
CAS Number2925081-83-8
SMILESO=C1NC(=O)CCN1C=2C=C(Br)C=3N=CN=CC3C2
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