CRBN ligand-319

Catalog No.: A81209
Ligand for E3 Ligase
CRBN ligand-319 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be connected to a target protein ligand through a suitable linker to create a proteolysis-targeting chimera (PROTAC), enabling selective degradation of specific proteins. It serves as a valuable tool in the study of targeted protein degradation and has potential applications in drug discovery and therapeutic development.
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5mg
10mg
50mg
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Adooq Products cited in reputable paper
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Biological Activity
DescriptionCRBN ligand-319 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be connected to a target protein ligand through a suitable linker to create a proteolysis-targeting chimera (PROTAC), enabling selective degradation of specific proteins. It serves as a valuable tool in the study of targeted protein degradation and has potential applications in drug discovery and therapeutic development.
Product Information
Catalog NumA81209
FormulaC12H11N5O2
Molecular Weight257.25
CAS Number2925078-15-3
SMILESO=C1NC(=O)CCN1C=2C=CC=3C(=NN=CC3C2)N
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