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CRBN ligand-325

Ligand for E3 Ligase

CRBN ligand-325 is a ligand specific for the E3 ubiquitin ligase cereblon (CRBN). This compound facilitates the recruitment of the CRBN protein, enabling targeted protein degradation through the formation of PROTACs when linked to a target protein ligand via a suitable linker. It is valuable for applications in ubiquitination research and drug discovery strategies aimed at modulating protein levels within cells.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925070-37-5
Applications	Ligand for E3 Ligase
Formula	C₁₂H₉BrN₄O₂
Molecular Weight	321.13
SMILES	O=C1NC(=O)CCN1C=2C=C(Br)C=3C=NN=CC3C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.