CRBN ligand-333

Catalog No.: A80685
Ligand for E3 Ligase
CRBN Ligand-333 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This chemical compound is designed to be conjugated with a target protein ligand through a linker, enabling the formation of proteolysis-targeting chimeras (PROTACs). Its application in targeted protein degradation research offers significant potential for therapeutic intervention and advancing drug discovery initiatives.
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Adooq Products cited in reputable paper
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Biological Activity
DescriptionCRBN Ligand-333 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This chemical compound is designed to be conjugated with a target protein ligand through a linker, enabling the formation of proteolysis-targeting chimeras (PROTACs). Its application in targeted protein degradation research offers significant potential for therapeutic intervention and advancing drug discovery initiatives.
Product Information
Catalog NumA80685
FormulaC12H9ClN4O2
Molecular Weight276.68
CAS Number2925102-76-5
SMILESO=C1NC(=O)CCN1C2=CC=CC3=CN=C(Cl)N=C32
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