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CRBN ligand-337

Ligand for E3 Ligase

CRBN ligand-337 is an E3 ubiquitin ligase ligand that specifically interacts with cereblon (CRBN). This compound facilitates the recruitment of CRBN, enabling the creation of proteolysis-targeting chimeras (PROTACs) when conjugated with a target protein ligand through a linker. CRBN ligand-337 is instrumental in drug discovery and research focused on targeted protein degradation pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925102-25-4
Applications	Ligand for E3 Ligase
Formula	C₁₃H₁₂N₄O₂
Molecular Weight	256.27
SMILES	O=C1NC(=O)CCN1C=2C=CC=3C(=NC=CC3C2)N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.