CRBN ligand-338 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to specific target proteins. By utilizing a linker, CRBN ligand-338 can be employed to create PROTACs (proteolysis-targeting chimeras), enabling targeted degradation of intracellular proteins. This compound serves as a valuable tool for research applications in protein homeostasis, targeted protein degradation, and drug discovery.
CRBN ligand-338 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to specific target proteins. By utilizing a linker, CRBN ligand-338 can be employed to create PROTACs (proteolysis-targeting chimeras), enabling targeted degradation of intracellular proteins. This compound serves as a valuable tool for research applications in protein homeostasis, targeted protein degradation, and drug discovery.
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