Documents & Downloads

CRBN ligand-338

Ligand for E3 Ligase

CRBN ligand-338 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to specific target proteins. By utilizing a linker, CRBN ligand-338 can be employed to create PROTACs (proteolysis-targeting chimeras), enabling targeted degradation of intracellular proteins. This compound serves as a valuable tool for research applications in protein homeostasis, targeted protein degradation, and drug discovery.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925101-90-0
Applications	Ligand for E3 Ligase
Formula	C₁₃H₁₂N₄O₂
Molecular Weight	256.27
SMILES	O=C1NC(=O)CCN1C2=CC=CC=3C(=NC=CC32)N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.