Documents & Downloads

CRBN ligand-340

Ligand for E3 Ligase

CRBN ligand-340 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN). It facilitates the recruitment of the CRBN protein, allowing for the targeted degradation of specific proteins through the formation of PROTAC molecules when conjugated to a target protein ligand via a linker. This compound is useful in research applications exploring protein degradation pathways and therapeutic strategies that harness the ubiquitin-proteasome system.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925099-57-4
Applications	Ligand for E3 Ligase
Formula	C₁₃H₁₀BrN₃O₂
Molecular Weight	320.15
SMILES	O=C1NC(=O)CCN1C=2C=C(Br)C=C3C=CN=CC32

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.