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CRBN ligand-344

Ligand for E3 Ligase

CRBN Ligand-344 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be conjugated to a target protein ligand through a linker, enabling the development of PROTACs (proteolysis targeting chimeras). CRBN Ligand-344 is instrumental in targeted protein degradation research, providing valuable insights into protein regulation and therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925096-29-1
Applications	Ligand for E3 Ligase
Formula	C₁₃H₁₂N₄O₂
Molecular Weight	256.27
SMILES	O=C1NC(=O)CCN1C=2C=C(N)C=3C=CN=CC3C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.