CRBN ligand-352 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be conjugated to target protein ligands through a suitable linker, enabling the development of PROTACs (proteolysis-targeting chimeras). Its application in targeted protein degradation research provides a valuable tool for studying protein function and modulation in cellular pathways.
CRBN ligand-352 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be conjugated to target protein ligands through a suitable linker, enabling the development of PROTACs (proteolysis-targeting chimeras). Its application in targeted protein degradation research provides a valuable tool for studying protein function and modulation in cellular pathways.
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