CRBN ligand-353 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be utilized in the design of PROTACs (Proteolysis Targeting Chimeras) by covalently linking it to a target protein ligand via a suitable linker. It is valuable in studies focused on targeted protein degradation and modulation of cellular pathways mediated by ubiquitination.
CRBN ligand-353 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be utilized in the design of PROTACs (Proteolysis Targeting Chimeras) by covalently linking it to a target protein ligand via a suitable linker. It is valuable in studies focused on targeted protein degradation and modulation of cellular pathways mediated by ubiquitination.
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