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CRBN ligand-367

Ligand for E3 Ligase

CRBN ligand-367 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to specific target proteins. This compound can be utilized in the design of Proteolysis Targeting Chimeras (PROTACs) when linked to a target protein ligand through a suitable linker. CRBN ligand-367 is essential for studies involving targeted protein degradation and the modulation of protein function within cellular contexts.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925084-57-5
Applications	Ligand for E3 Ligase
Formula	C₁₁H₁₁N₅O₂
Molecular Weight	245.24
SMILES	O=C1NC(=O)CCN1C=2C=C(N)C=3C=NNC3C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.