CRBN ligand-373 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein to target proteins. This compound is designed to be covalently linked to target protein ligands through a linker, enabling the formation of proteolysis-targeting chimeras (PROTACs). Its application in targeted protein degradation research offers valuable insights into cellular processes and therapeutic interventions.
CRBN ligand-373 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein to target proteins. This compound is designed to be covalently linked to target protein ligands through a linker, enabling the formation of proteolysis-targeting chimeras (PROTACs). Its application in targeted protein degradation research offers valuable insights into cellular processes and therapeutic interventions.
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