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CRBN ligand-393

Ligand for E3 Ligase

CRBN ligand-393 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. It can be effectively linked to target protein ligands through a suitable linker to create a PROTAC, enabling targeted protein degradation. This compound is valuable for research applications focused on therapeutic interventions in cellular processes mediated by protein homeostasis.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2865157-07-7
Applications	Ligand for E3 Ligase
Formula	C₁₇H₂₀N₂O₃
Molecular Weight	300.36
SMILES	O=CC1CCN(C2=CC=CC(=C2)C3C(=O)NC(=O)CC3)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.