CRBN ligand-394

Catalog No.: A80491
Ligand for E3 Ligase
CRBN ligand-394 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound is instrumental in the development of PROTACs by enabling the conjugation of target protein ligands through a linker. Its utility extends to studies in targeted protein degradation and therapeutic applications.
Grouped product items
Size Price Stock Qty
5mg
$20.00
In stock
10mg
$35.00
In stock
25mg
$65.00
In stock
50mg
$100.00
In stock
100mg
$160.00
In stock
250mg
$345.00
In stock
500mg
$550.00
In stock
1g
$880.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCRBN ligand-394 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound is instrumental in the development of PROTACs by enabling the conjugation of target protein ligands through a linker. Its utility extends to studies in targeted protein degradation and therapeutic applications.
Product Information
Catalog NumA80491
FormulaC15H20ClN3O2
Molecular Weight309.79
CAS Number2641512-77-6
SMILESCl.O=C1NC(=O)C(C2=CC=C(C=C2)N3CCNCC3)CC1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2