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CRBN ligand-413

Ligand for E3 Ligase

CRBN ligand-413 is an E3 ubiquitin ligase ligand that specifically targets cereblon (CRBN). This compound facilitates the recruitment of the CRBN protein and can be utilized in the development of PROTACs by linking it to a target protein ligand through a suitable linker. Its applications are significant in studying targeted protein degradation and the modulation of protein levels within cellular contexts.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925101-91-1
Applications	Ligand for E3 Ligase
Formula	C₁₄H₁₁N₃O₃
Molecular Weight	269.26
SMILES	O=CC1=CN=C2C=CC=C(C2=C1)N3C(=O)NC(=O)CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.