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CRBN ligand-415

Ligand for E3 Ligase

CRBN ligand-415 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound is designed for the synthesis of PROTACs (Proteolysis Targeting Chimeras) by linking to specific target protein ligands via a suitable linker. Its utility in research includes the development of targeted protein degradation strategies, enabling the selective modulation of cellular protein levels for therapeutic intervention.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925101-06-8
Applications	Ligand for E3 Ligase
Formula	C₁₄H₁₁N₃O₃
Molecular Weight	269.26
SMILES	O=CC1=CN=C2C=C(C=CC2=C1)N3C(=O)NC(=O)CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.